Community observations, not medical advice.Always speak with a qualified healthcare professional.
nootropic

Bacopa Monnieri

Also known as Brahmi, Water Hyssop

Ayurvedic herb whose bacosides are thought to enhance dendritic branching and cholinergic signalling; trials of standardised extract taken for 8-12 weeks show modest improvements in memory recall.

Reported side effects:Mild side-effects reported by only 2.3% of all participants across trials of Bacopa monnieri in child and adolescent populations, where safety and tolerability data were well reported for 80% of included studies (systematic review, PMID 27912958)

Suspect a side effect? Report it to the MHRA Yellow Card scheme ↗

3linked conditions
22linked studies
Evidence

What the research actually shows

We link to relevant studies and leave interpretation to you and your healthcare professional.

What studies found

The headline results, condition by condition

The large figures are what the studies reported for each thing they measured. Open a card for every result.

Colour keyReported a benefitNo clear benefitUnclearPossible harmAmber is for highlights, such as where the most research is. It never means a result was good.

6of 9

Memory

6 of 9 results reported a benefit

3 studies, including a review of trials

  • Attention and short-term memoryNo clear benefit foundmeasurement not reportedBrahmi did not improve attention or verbal and visual short-term memory compared to placebo.1 randomised trial2002 study ↗

No figure given: Everyday memory and anxiety (no clear benefit); Delayed word recall (reported a benefit); Retention of new information (reported a benefit).

Also measured alongside: Task-switching time (reported a benefit); Reaction time (reported a benefit); Attention task performance (reported a benefit); and 2 more.

Every result
Safety

Safety and considerations

What sources report about side effects, who should be careful, and medicines to ask about first.

Reported side effects

Reported effectHow oftenBasisSources
Mild side-effects reported by only 2.3% of all participants across trials of Bacopa monnieri in child and adolescent populations, where safety and tolerability data were well reported for 80% of included studies (systematic review, PMID 27912958)commonListed by PubMed corpus rows (PubMed 27912958)Kean JD, Downey LA, Stough C. A systematic review of the Ayurvedic medicinal herb Bacopa monnieri in child and adolescent populations. Complement Ther Med 2016;29:56-62 (PMID 27912958)
Evidence analytics

Where the evidence is concentrated

Audited published research for Bacopa Monnieri by condition. Drill into a pair page for the full breakdown.

Published research

Bacopa Monnieri: findings by condition

What this means: Bars count reported findings, not treatment effectiveness or certainty.

One study may report several findings or appear in more than one pairing. Counts do not show the size of an effect. Comparable numerical estimates are not established for this summary.

View the full data table
Published research: reported directions by pairing
Compound and conditionFindings (count)Studies (count)Reported results (finding counts)How sure?
Memory93Benefit: 6; no benefit: 3; harm: 0; unclear: 0; not recorded / unrecognised: 0Not formally graded

Suggested uses (unproven)

Where people report using it and what trials suggest

  • Moderate evidenceMemory consolidation (older adults, 12w+ dosing)
  • Weak evidenceAnxiety (mild)

Where the evidence is negative

Common claims the trials do not support

  • Effects absent in several trials and minimal in healthy young adults.
  • Onset takes 8-12 weeks — acute-focus marketing is wrong.
  • Small samples and industry funding common.

Ayurvedic herb with delayed-onset memory benefits in small trials (12-week timelines); modern replication is thin.

Evidence grades reflect study quality and consistency, not marketing claims.

22studies referenced
17journals
2001–2026publication range

Ordered by strength of evidence, then result direction.

01Comparative effects of Bacopa monnieri and Ginkgo biloba on cognitive functions: A systematic review and network meta-analysisTiemtad P, et al. · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2026PMID 41678913 ↗02Efficiency of Different Supplements in Alleviating Symptoms of ADHD with or Without the Use of Stimulants: A Systematic ReviewAl Shahab S, et al. · Nutrients · 2025PMID 40362791 ↗03Therapeutic Evaluation of Unani Medicine, Including Single Drugs and Polyherbal Formulations with Special Reference to Neurodegenerative DisordersImran S, et al. · Alternative therapies in health and medicine · 2024PMID 39212516 ↗04Plant-derived nootropics and human cognition: A systematic reviewLorca C, et al. · Critical reviews in food science and nutrition · 2023PMID 34978226 ↗05A systematic review of the Ayurvedic medicinal herb Bacopa monnieri in child and adolescent populationsKean JD, et al. · Complementary therapies in medicine · 2016PMID 27912958 ↗06Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extractKongkeaw C, et al. · Journal of ethnopharmacology · 2014PMID 24252493 ↗
Show all 22 studies
07The cognitive-enhancing effects of Bacopa monnieri: a systematic review of randomized, controlled human clinical trialsPase MP, et al. · Journal of alternative and complementary medicine (New York, N.Y.) · 2012PMID 22747190 ↗08Herbal remedies for anxiety - a systematic review of controlled clinical trialsErnst E · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2006PMID 16428031 ↗09The Effects of a Bacopa monnieri Extract (Bacumen(®)) on Cognition, Stress, and Fatigue in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled TrialLopresti AL, et al. · Clinical drug investigation · 2025PMID 41091332 ↗10Bacopa monnieri in Patients with Parkinson's Disease: A Pilot StudySantos AFD, et al. · Journal of medicinal food · 2023PMID 36800346 ↗11Investigating the Effects of a Multinutrient Supplement on Cognition, Mood and Biochemical Markers in Middle-Aged Adults with 'Optimal' and 'Sub-Optimal' Diets: A Randomized Double Blind Placebo Controlled TrialYoung LM, et al. · Nutrients · 2022PMID 36501109 ↗12An acute, double-blind, placebo-controlled cross-over study of 320 mg and 640 mg doses of Bacopa monnieri (CDRI 08) on multitasking stress reactivity and moodBenson S, et al. · Phytotherapy research : PTR · 2014PMID 23788517 ↗13Brahmi for the better? New findings challenging cognition and anti-anxiety effects of Brahmi (Bacopa monniera) in healthy adultsSathyanarayanan V, et al. · Psychopharmacology · 2013PMID 23354535 ↗14Clinical efficacy of Manasamitra Vataka (an Ayurveda medication) on generalized anxiety disorder with comorbid generalized social phobia: a randomized controlled studyTubaki BR, et al. · Journal of alternative and complementary medicine (New York, N.Y.) · 2012PMID 22784349 ↗15Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly: a randomized, double-blind, placebo-controlled trialCalabrese C, et al. · Journal of alternative and complementary medicine (New York, N.Y.) · 2008PMID 18611150 ↗16Chronic effects of Brahmi (Bacopa monnieri) on human memoryRoodenrys S, et al. · Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2002PMID 12093601 ↗17The chronic effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy human subjectsStough C, et al. · Psychopharmacology · 2001PMID 11498727 ↗18Neurobehavioural Exploration of Breath-counting & Breath-awareness in Novice Indian Meditators: A Naturalised Ānāpānasati-based Paradigmatic ApproachBrahmi M, et al. · Annals of neurosciences · 2025PMID 39850443 ↗19Mentha pulegium L. and Salvia officinalis L. Bioactive Compounds: Focus on Their Application in Agriculture and Food PackagingKhodja NK, et al. · Chemistry & biodiversity · 2025PMID 39903845 ↗20In Vitro Antiviral Activity of Potential Medicinal Plant Extracts Against Dengue and Chikungunya VirusesAlagarasu K, et al. · Frontiers in cellular and infection microbiology · 2022PMID 35463636 ↗21Ameliorative Effects of Phytomedicines on Alzheimer's PatientsKhandia R, et al. · Current Alzheimer research · 2022PMID 35692129 ↗22The Safety and Efficacy of Botanicals with Nootropic EffectsRoe AL, et al. · Current neuropharmacology · 2021PMID 34315377 ↗

Published research results

Reported results grouped by condition. Values and units are preserved as recorded; missing information is not estimated.

How to read this table

Benefit
What the trial saw happen: whether the measured outcome moved in the helpful direction in that one study (the tag on each row: “Benefit seen”, “No clear benefit”, “Possible harm” or “Unclear”). It is a study result — not advice, and not a promise it will work for you.
Evidence
Study design describes how research was conducted. It is not a formal certainty assessment.
Effect size
The result recorded in this summary. “Not reported” means the value is missing from the summary; it does not establish that the publication omitted it.

Reported direction, numerical results and study design are separate. Certainty has not been formally graded in this table.

Memory (9 outcomes)
Published research: Memory
What was measuredReported findingsResult and unitsReported sample and durationStudy / source
Choice reaction timeBacopa reduced choice reaction time compared to placebo; the abstract reports 10.6 ms, with a negative confidence interval. (95% CI -12.1 to -9.2; p<0.001)Benefit seen10.6 ms
Recorded unit: ms
Sample (as reported): 437
Follow-up: 12 weeks
Meta-analysis · 2014
Study details
Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract.
Meta-Analysis
PMID 24252493
Trail B test timeBacopa shortened Trail B test time compared to placebo, with a reported difference of -17.9 ms. (95% CI -24.6 to -11.2; p<0.001)Benefit seen-17.9 ms
Recorded unit: ms
Sample (as reported): 437
Follow-up: 12 weeks
Meta-analysis · 2014
Study details
Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract.
Meta-Analysis
PMID 24252493
delayed word recall memory (AVLT)Bacopa monnieri improved delayed word recall memory (AVLT) compared with placebo in older adults over 12 weeks (n=48).Benefit seenNot reported
Recorded unit: Not reported
Sample (as reported): 48
Follow-up: 12 weeks
Randomised trial · 2008
Study details
Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly: a randomized, double-blind, placebo-controlled trial.
Randomized Controlled Trial
PMID 18611150
depression (CESD-10) and anxiety (STAI) scoresDepression and anxiety scores improved with Bacopa monnieri but worsened with placebo over 12 weeks in older adults (n=48).Benefit seenNot reported
Recorded unit: Not reported
Sample (as reported): 48
Follow-up: 12 weeks
Randomised trial · 2008
Study details
Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly: a randomized, double-blind, placebo-controlled trial.
Randomized Controlled Trial
PMID 18611150
Divided Attention Task, WAIS digit task, mood, blood pressureBacopa monnieri showed no effect on divided attention, working memory, mood, or blood pressure compared with placebo (n=48).No clear benefitNot reported
Recorded unit: Not reported
Sample (as reported): 48
Follow-up: 12 weeks
Randomised trial · 2008
Study details
Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly: a randomized, double-blind, placebo-controlled trial.
Randomized Controlled Trial
PMID 18611150
Stroop Task performanceStroop task performance improved with Bacopa monnieri while the placebo group showed no change over 12 weeks (n=48).Benefit seenNot reported
Recorded unit: Not reported
Sample (as reported): 48
Follow-up: 12 weeks
Randomised trial · 2008
Study details
Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly: a randomized, double-blind, placebo-controlled trial.
Randomized Controlled Trial
PMID 18611150
Attention and short-term memoryBrahmi did not improve attention or verbal and visual short-term memory compared to placebo.No clear benefitNot reported
Recorded unit: Not reported
Sample (as reported): Seventy-six
Follow-up: three months
Randomised trial · 2002
Study details
Chronic effects of Brahmi (Bacopa monnieri) on human memory.
Randomized Controlled Trial
PMID 12093601
Everyday memory and anxietyBrahmi did not improve questionnaire measures of everyday memory or anxiety compared to placebo.No clear benefitNot reported
Recorded unit: Not reported
Sample (as reported): Seventy-six
Follow-up: three months
Randomised trial · 2002
Study details
Chronic effects of Brahmi (Bacopa monnieri) on human memory.
Randomized Controlled Trial
PMID 12093601
Retention of newly learned informationBrahmi improved retention of new information compared to placebo; the abstract gives no effect size.Benefit seenNot reported
Recorded unit: Not reported
Sample (as reported): Seventy-six
Follow-up: three months
Randomised trial · 2002
Study details
Chronic effects of Brahmi (Bacopa monnieri) on human memory.
Randomized Controlled Trial
PMID 12093601
Important: This page reflects observational, aggregate-only community reporting and independent published research. It is not medical advice, and it does not claim any compound treats, cures, or is effective for any condition. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or treatment.
Outcomes & conditions

Why people look into Bacopa Monnieri — and what they report

Associated conditions and community-reported outcomes, wrapped together on one page. Aggregates appear only once enough reports arrive.

Outcomes & conditions →
Important: This page reflects observational, aggregate-only community reporting and independent published research. It is not medical advice, and it does not claim any compound treats, cures, or is effective for any condition. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or treatment.
Availability

Where to get Bacopa Monnieri (UK)

How this compound is sold in the UK, and where our readers typically find it.

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