Cannabis (THC) for Epilepsy
Delta-9-tetrahydrocannabinol, the primary psychoactive cannabinoid in Cannabis sativa, acting as a partial agonist at CB1 receptors; used medically for chronic pain, chemotherapy-induced nausea, appetite stimulation, and spasticity. Subject to legal restrictions varying by jurisdiction.
The connection
Neurological disorder characterised by recurrent seizures. Some cannabinoids have established anti-seizure efficacy for specific syndromes.
Also known as: THC, Delta-9-tetrahydrocannabinol, Marijuana, Cannabis sativa
Cannabis (THC) × Epilepsy: at a glance
Every published result for this pair, extracted and audited.
Cannabis (THC) / Epilepsy: publication years
What this means: Counts describe research quantity, not treatment effectiveness or certainty.
| Category | Publications (count) |
|---|---|
| 2023 | 1 |
| 2024 | 2 |
| 2026 | 3 |
Cannabis (THC) × Epilepsy: the evidence base
Hand-selected PubMed studies, linked to the originals.
Ordered by strength of evidence, then result direction.
01Cannabis-Based Products for Chronic Pain : An Updated Systematic ReviewChou R, et al. · Annals of internal medicine · 2026PMID 41429020 ↗02Cannabidiol Use in Developmental and Epileptic Encephalopathies: A Syndrome- and Age-Stratified Systematic Review and Meta-analysisde Oliveira HM, et al. · CNS drugs · 2026PMID 42185726 ↗03The effects of oral cannabidiol supplementation on blood pressure in adults: a systematic review of randomised controlled trialsRoberts A, et al. · Journal of cannabis research · 2026PMID 42321899 ↗04Effectiveness of Cannabidiol to Manage Chronic Pain: A Systematic ReviewMohammed SYM, et al. · Pain management nursing : official journal of the American Society of Pain Management Nurses · 2024PMID 37953193 ↗05Cannabis and Cannabinoids in Adults With Cancer: ASCO GuidelineBraun IM, et al. · Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024PMID 38478773 ↗06Evidence-Based Treatment of Pain in Chemotherapy-Induced Peripheral NeuropathyD'Souza RS, et al. · Current pain and headache reports · 2023PMID 37058254 ↗Community experiences
Contributors volunteered; this does not establish treatment effectiveness or population incidence.
Reported changes
No publishable community breakdown is available. This does not establish that no reports exist.