| Fasting glucose | Fenugreek lowered fasting glucose compared to control interventions, with a mean change difference of -0.96 mmol/l. (95% CI: -1.52, -0.40)Benefit seen | -0.96 mmol/l Recorded unit: mmol/l | Sample (as reported): Not reported Follow-up: Not reported | Meta-analysis · 2014 Study detailsEffect of fenugreek (Trigonella foenum-graecum L.) intake on glycemia: a meta-analysis of clinical trials. Meta-Analysis PMID 24438170 |
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| HbA1c | Fenugreek lowered HbA1c compared to control interventions, with a mean change difference of -0.85%. (95% CI: -1.49%, -0.22%)Benefit seen | -0.85% mean change difference Recorded unit: % | Sample (as reported): Not reported Follow-up: Not reported | Meta-analysis · 2014 Study detailsEffect of fenugreek (Trigonella foenum-graecum L.) intake on glycemia: a meta-analysis of clinical trials. Meta-Analysis PMID 24438170 |
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| Postload glucose | Fenugreek lowered postload glucose compared to control interventions, with a mean change difference of -2.19 mmol/l. (95% CI: -3.19, -1.19)Benefit seen | -2.19 mmol/l Recorded unit: mmol/l | Sample (as reported): Not reported Follow-up: Not reported | Meta-analysis · 2014 Study detailsEffect of fenugreek (Trigonella foenum-graecum L.) intake on glycemia: a meta-analysis of clinical trials. Meta-Analysis PMID 24438170 |
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| HbA(1c) with fenugreek | Fenugreek lowered HbA(1c) compared to placebo, with a mean difference of -1.13%. (95% CI -0.11% to -2.14%; P = 0.03)Benefit seen | -1.13% mean difference Recorded unit: % | Sample (as reported): Not reported Follow-up: Not reported | Meta-analysis · 2011 Study detailsMeta-analysis of the effect of herbal supplement on glycemic control in type 2 diabetes. Meta-Analysis PMID 21843614 |
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| fasting blood glucose (FBG) | Fenugreek reduced fasting blood glucose by SMD -19.64 vs placebo in 3130 people. (p < 0.05)Benefit seen | -19.64 SMD Recorded unit: Not reported | Sample (as reported): 3130 Follow-up: Not reported | Systematic review · 2023 Study detailsComparative effectiveness of six herbs in the management of glycemic status of type 2 diabetes mellitus patients: A systematic review and network meta-analysis of randomized controlled trials. Systematic Review PMID 37451111 |
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| HbA1C | Fenugreek seeds reduced HbA1C by SMD 0.84 vs placebo in 3130 people.Benefit seen | 0.84 SMD Recorded unit: Not reported | Sample (as reported): 3130 Follow-up: Not reported | Systematic review · 2023 Study detailsComparative effectiveness of six herbs in the management of glycemic status of type 2 diabetes mellitus patients: A systematic review and network meta-analysis of randomized controlled trials. Systematic Review PMID 37451111 |
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| 2 h plasma glucose during OGTT (2-hPG) | Fenugreek significantly reduced 2-hour plasma glucose compared to control in 706 participants.Benefit seen | Not reported Recorded unit: Not reported | Sample (as reported): 706 Follow-up: Not reported | Systematic review · 2023 Study detailsThe Effect of Fenugreek in Type 2 Diabetes and Prediabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Systematic Review PMID 37762302 |
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| Body mass index (BMI) | Fenugreek showed no significant difference in BMI compared to control in 706 participants.No clear benefit | Not reported Recorded unit: Not reported | Sample (as reported): 706 Follow-up: Not reported | Systematic review · 2023 Study detailsThe Effect of Fenugreek in Type 2 Diabetes and Prediabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Systematic Review PMID 37762302 |
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| Fasting blood glucose (FBG) | Fenugreek significantly reduced fasting blood glucose compared to control in 706 participants.Benefit seen | Not reported Recorded unit: Not reported | Sample (as reported): 706 Follow-up: Not reported | Systematic review · 2023 Study detailsThe Effect of Fenugreek in Type 2 Diabetes and Prediabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Systematic Review PMID 37762302 |
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| Glycosylated hemoglobin (HbA1c) | Fenugreek significantly reduced HbA1c compared to control in 706 participants.Benefit seen | Not reported Recorded unit: Not reported | Sample (as reported): 706 Follow-up: Not reported | Systematic review · 2023 Study detailsThe Effect of Fenugreek in Type 2 Diabetes and Prediabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Systematic Review PMID 37762302 |
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| High density lipoprotein (HDL-C) | Fenugreek significantly improved HDL-C compared to control in 706 participants.Benefit seen | Not reported Recorded unit: Not reported | Sample (as reported): 706 Follow-up: Not reported | Systematic review · 2023 Study detailsThe Effect of Fenugreek in Type 2 Diabetes and Prediabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Systematic Review PMID 37762302 |
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| Homeostatic model assessment for insulin resistance (HOMA-IR) | Fenugreek did not significantly decrease HOMA-IR compared to control in 706 participants.No clear benefit | Not reported Recorded unit: Not reported | Sample (as reported): 706 Follow-up: Not reported | Systematic review · 2023 Study detailsThe Effect of Fenugreek in Type 2 Diabetes and Prediabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Systematic Review PMID 37762302 |
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| Low density lipoprotein (LDL-C) | Fenugreek showed no significant difference in LDL-C compared to control in 706 participants.No clear benefit | Not reported Recorded unit: Not reported | Sample (as reported): 706 Follow-up: Not reported | Systematic review · 2023 Study detailsThe Effect of Fenugreek in Type 2 Diabetes and Prediabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Systematic Review PMID 37762302 |
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| Total cholesterol (TC) | Fenugreek significantly improved total cholesterol compared to control in 706 participants.Benefit seen | Not reported Recorded unit: Not reported | Sample (as reported): 706 Follow-up: Not reported | Systematic review · 2023 Study detailsThe Effect of Fenugreek in Type 2 Diabetes and Prediabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Systematic Review PMID 37762302 |
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| Triglyceride (TG) | Fenugreek significantly improved triglycerides compared to control in 706 participants.Benefit seen | Not reported Recorded unit: Not reported | Sample (as reported): 706 Follow-up: Not reported | Systematic review · 2023 Study detailsThe Effect of Fenugreek in Type 2 Diabetes and Prediabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Systematic Review PMID 37762302 |
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| Glycemic control (best evidence among Iranian antidiabetic plants) | Among Iranian antidiabetic plants tested in RCTs, Trigonella foenum-graecum showed the best evidence for glycemic control vs control.Benefit seen | Not reported Recorded unit: Not reported | Sample (as reported): Not reported Follow-up: Not reported | Systematic review · 2011 Study detailsAntidiabetic plants of Iran. Systematic Review PMID 22071637 |
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| High-density lipoprotein cholesterol | HDL cholesterol increased by 21.7% vs metformin in 57 patients over one month. (P < 0.001)Benefit seen | 21.7% Recorded unit: Not reported | Sample (as reported): 57 Follow-up: one month | Randomised trial · 2019 Study detailsAntidiabetic Effect of Fenugreek Seed Powder Solution (Trigonella foenum-graecum L.) on Hyperlipidemia in Diabetic Patients. Randomized Controlled Trial PMID 31583253 |
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| Low-density lipoprotein cholesterol | LDL cholesterol decreased by 23.4% vs metformin in 57 patients over one month. (P < 0.001)Benefit seen | 23.4% Recorded unit: Not reported | Sample (as reported): 57 Follow-up: one month | Randomised trial · 2019 Study detailsAntidiabetic Effect of Fenugreek Seed Powder Solution (Trigonella foenum-graecum L.) on Hyperlipidemia in Diabetic Patients. Randomized Controlled Trial PMID 31583253 |
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| Total cholesterol | Total cholesterol decreased by 13.6% vs metformin in 57 patients over one month. (P < 0.001)Benefit seen | 13.6% Recorded unit: Not reported | Sample (as reported): 57 Follow-up: one month | Randomised trial · 2019 Study detailsAntidiabetic Effect of Fenugreek Seed Powder Solution (Trigonella foenum-graecum L.) on Hyperlipidemia in Diabetic Patients. Randomized Controlled Trial PMID 31583253 |
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| Triglyceride | Triglycerides decreased by 23.53% vs metformin in 57 patients over one month. (P < 0.05)Benefit seen | 23.53% Recorded unit: Not reported | Sample (as reported): 57 Follow-up: one month | Randomised trial · 2019 Study detailsAntidiabetic Effect of Fenugreek Seed Powder Solution (Trigonella foenum-graecum L.) on Hyperlipidemia in Diabetic Patients. Randomized Controlled Trial PMID 31583253 |
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