Compound library
Understand what people are taking.
Browse medicines, supplements, herbs, and health foods. Each profile brings community reports and linked research into one clear view.
Browse medicines, supplements, herbs, and health foods. Each profile brings community reports and linked research into one clear view.
The simplest amino acid: an inhibitory brain messenger and a building block of collagen and glutathione. Human evidence is thin. Small trials report better sleep and less next-day tiredness with 3 g at bedtime, and one 74-person trial lowered HbA1c in type 2 diabetes, but a 2024 systematic review rates the sleep studies as small with a high risk of bias. 'GlyNAC' trials combine it with NAC, so they cannot show what glycine does alone.
1 of 1 result reported a benefit, from 1 published study.
1 randomised trial, 14 people
These are the figures the studies reported, not a prediction for any one person. Where several studies measured the same thing in the same unit, we show a simple average and say so. Every individual result is listed below.
See every resultObsessive-compulsive disorder. Intrusive thoughts and repetitive behaviours that are difficult to control.
Also known as: Glycine supplement
Every published result for this pair, extracted and audited.
These charts group published studies by what they reported and how they were run — green marks studies that reported a benefit for this pairing. Tiers run from pooled analyses of many trials (strongest) to one-off observational reports.
Direction of reported outcomes for Glycine in ocd.
Study designs behind these findings.
Every measured outcome, one row per finding - numbers exactly as reported.
| Study | Design | n | Duration | Outcome measured | Reported result | Direction |
|---|---|---|---|---|---|---|
| PMID 19046587 2009 | Randomised trial | 14 | 12 weeks | Y-BOCS score change | 6.04 points | Benefit |
Hand-selected PubMed studies, linked to the originals.
Ordered by strength of evidence, then result direction.
01The safety and efficacy of N-acetylcysteine as an augmentation in the treatment of obsessive-compulsive disorder in adults: a systematic review and meta-analysis of randomized clinical trialsEghdami S, et al. · Frontiers in psychiatry · 2024PMID 39376972 ↗02Brazilian Research Consortium on Obsessive-Compulsive Spectrum Disorders guidelines for the treatment of adult obsessive-compulsive disorder. Part I: pharmacological treatmentde Oliveira MVS, et al. · Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2023PMID 36749887 ↗03Clinical Recommendations for Augmentation Agents in Obsessive-Compulsive Disorder Partially Responsive to Serotonin Reuptake InhibitorsGautam M · Journal of clinical psychopharmacology · 2023PMID 37335203 ↗04Pharmacotherapy for trichotillomaniaHoffman J, et al. · The Cochrane database of systematic reviews · 2021Be the first to share what you noticed with Glycine for ocd. Why counts start empty.