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supplement × Hormone Health

Phosphatidylserine for Cortisol Management

Phospholipid concentrated in neuronal cell membranes, now typically sourced from soy or sunflower lecithin; small trials suggest a reduced cortisol response to exercise stress and modest cognitive benefit in age-related decline.

-published research: study records
-published research: findings
Not formally gradedcertainty of the research
On this pageOverviewEvidenceCommunity outcomesRelated
Why Phosphatidylserine for Cortisol Management?

The connection

Regulating the body's primary stress hormone. Chronic elevation affects sleep, weight, immune function, and mood.

Also known as: PS, Soy phosphatidylserine

Published research

Phosphatidylserine × Cortisol Management: at a glance

Every published result for this pair, extracted and audited.

Published research

Phosphatidylserine / Cortisol Management: publication years

What this means: Counts describe research quantity, not treatment effectiveness or certainty.

Phosphatidylserine / Cortisol Management: publication years (publications, count)
CategoryPublications (count)
20244
20252
← Zoom out: all evidence for PhosphatidylserineZoom out: compare compounds for Cortisol Management →
Published research

Phosphatidylserine × Cortisol Management: the evidence base

Hand-selected PubMed studies, linked to the originals.

6studies referenced
6journals
2024–2025publication range

Ordered by strength of evidence, then result direction.

01Effects of acute exercise on cognitive function: A meta-review of 30 systematic reviews with meta-analysesChang YK, et al. · Psychological bulletin · 2025PMID 39883421 ↗02Piriformis syndrome: a systematic review of case reportsMonteleone G, et al. · BMC surgery · 2025PMID 41068685 ↗03Recent advances and controversial issues in the optimal management of asymptomatic carotid stenosisParaskevas KI, et al. · Journal of vascular surgery · 2024PMID 37939746 ↗04Impact of one night of sleep restriction on sleepiness and cognitive function: A systematic review and meta-analysisWüst LN, et al. · Sleep medicine reviews · 2024PMID 38759474 ↗05The effectiveness of visual-based interventions on health literacy in health care: a systematic review and meta-analysisGalmarini E, et al. · BMC health services research · 2024PMID 38862966 ↗06A systematic review and meta-analysis of cortisol levels in Plasmodium infectionsKotepui KU, et al. · Scientific reports · 2024PMID 39107355 ↗
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Community experiences

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Reported changes

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Important: This page reflects observational, aggregate-only community reporting and independent published research. It is not medical advice, and it does not claim any compound treats, cures, or is effective for any condition. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or treatment.