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Also known as Ganoderma lucidum, Lingzhi
Polypore fungus containing triterpenes and beta-glucans studied for immunomodulatory and calming effects; used traditionally in East Asian medicine to support sleep and reduce stress.
We link to relevant studies and leave interpretation to you and your healthcare professional.
Number of audited published findings for Reishi Mushroom by condition. Drill into a pair page for the full breakdown.
Where people report using it and what trials suggest
Common claims the trials do not support
'Mushroom of immortality' with immune-biomarker effects but little human endpoint evidence and real safety caveats for extracts.
Safety notes: Powdered extracts have caused hepatotoxicity in case series; anticoagulant effect; avoid pre-surgery and in pregnancy.
Evidence grades reflect study quality and consistency, not marketing claims.
Summaries of published trial results for this compound, grouped by condition. Numbers are reported exactly as the researchers published them — we never calculate or convert.
How to read this table
In short: benefit is what was observed; evidence is how much you should trust the observation. A “Benefit seen” tag on a weak study counts for far less than the same tag on a meta-analysis.
| Outcome measured | What trials found | Effect size | People studied | Duration | Type of evidence | Study |
|---|---|---|---|---|---|---|
| CD4+/CD8+ ratio | High-dose Ganoderma showed a nonsignificant trend toward preserving the lymphocyte ratio compared to placebo during altitude training.No clear benefit | no number reported | Forty | 28 days | RCT · 2008 | PMID 18048435 |
| Outcome measured | What trials found | Effect size | People studied | Duration | Type of evidence | Study |
|---|---|---|---|---|---|---|
| Antioxidant and immune markers |
Associated conditions and community-reported outcomes, wrapped together on one page. Aggregates appear only once enough reports arrive.
How this compound is sold in the UK, and where our readers typically find it.
Retailer search links — we may earn commission on purchases at no cost to you. Commission never affects our evidence ratings.
| Ganoderma did not significantly change antioxidant status or lymphocyte subsets compared to placebo.No clear benefit |
| no number reported |
| twenty-three |
| 12 weeks |
| RCT · 2012 |
| PMID 21801467 |
| Blood lipids | Ganoderma improved triglycerides and HDL compared to placebo in the first period, but carry-over effects prevented complete analysis.Unclear | no number reported | twenty-three | 12 weeks | RCT · 2012 | PMID 21801467 |
| BMI and blood pressure | Ganoderma did not change BMI or blood pressure compared to placebo.No clear benefit | no number reported | twenty-three | 12 weeks | RCT · 2012 | PMID 21801467 |
| Insulin resistance | Ganoderma lowered insulin and insulin resistance compared to placebo; the abstract gives no effect size.Benefit seen | no number reported | twenty-three | 12 weeks | RCT · 2012 | PMID 21801467 |