Immune & Detox

Allergies

About Allergies — Immune & Detox.

Immune overreaction to harmless substances — pollen, dust, food. Causes sneezing, itching, congestion, or skin reactions.

3studies analysed

1compounds with evidence

Randomised trialstrongest evidence

Where research is strongest

Spirulina 55

Add your outcome — free & pseudonymous

Tried something for Allergies? Share how it went — only ever published as part of a group of 10+.

4linked compounds

0linked studies

0published community reports

Results By the numbers Community Research Compounds

Headline results for Allergies.

Figures as the studies reported them.

Colour keyReported a benefitNo clear benefitUnclearPossible harmAmber is for highlights, such as where the most research is. It never means a result was good.

Spirulina

10 of 12 results reported a benefit

3 randomised trials, 53 people

Daily activity and sleep with allergiesReported a benefitsee exact figuresSpirulina platensis improved Sleep condition, daily working and social activity compared with cetirizine in 53 (2 months).1 randomised trial2020 study ↗

No figure given: Allergic rhinitis symptoms (reported a benefit); Nasal obstruction (reported a benefit); Rhinorrhoea prevalence (reported a benefit); Smell reduction (reported a benefit).

Also measured alongside: Blood interleukin-4 (IL-4) (reported a benefit); Blood interleukin-10 (IL-10) (reported a benefit); Blood interleukin-1α (IL-1α) (reported a benefit); and 3 more.

Every result

Where the evidence is concentrated.

Published research

Allergies: findings by compound

What this means: Bars count reported findings, not treatment effectiveness or certainty.

One study may report several findings or appear in more than one pairing. Counts do not show the size of an effect. Comparable numerical estimates are not established for this summary.

View the full data table

Published research: reported directions by pairing
Compound and condition	Findings (count)	Studies (count)	Reported results (finding counts)	How sure?
Spirulina	12	3	Benefit: 10; no benefit: 2; harm: 0; unclear: 0; not recorded / unrecognised: 0	Not formally graded

Degree of benefit for Allergies

Strongest evidence first.

Published research: Allergies. Study design is not a certainty grade.
Compound	Study designs	Reported findings
SpirulinaResearch score 55/100 · Moderate	3 randomised trials — 3 studies	10/12 outcomes showed benefit IL-4 levels32% reductionbenefit2005 study ↗ Exact figures 32% · Follow-up: 12 weeks · Sample (as reported): Not reported · Recorded unit: Not reported · Effects of a Spirulina-based dietary supplement on cytokine production from allergic rhinitis patients · Randomized Controlled Trial · rct · PMID 15857205 Interleukin-10 (IL-10) levels — a signal that drives inflammationReported a benefit — measurement not reportedbenefit2020 study ↗ Exact figures n=53 · Follow-up: 2 months · Sample (as reported): 53 · Recorded unit: Not reported · Clinical comparison of the efficacy of spirulina platensis and cetirizine for treatment of allergic rhinitis · Randomized Controlled Trial · rct · PMID 32773785 Interleukin-1α (IL-1α) levels — a signal that drives inflammationReported a benefit — see exact figuresbenefit2020 study ↗ Exact figures (P < 0.001) n=53 · Follow-up: 2 months · Sample (as reported): 53 · Recorded unit: Not reported · Clinical comparison of the efficacy of spirulina platensis and cetirizine for treatment of allergic rhinitis · Randomized Controlled Trial · rct · PMID 32773785 Interleukin-1β (IL-1β) levels — a signal that drives inflammationReported a benefit — see exact figuresbenefit2020 study ↗ Exact figures (P < 0.001) n=53 · Follow-up: 2 months · Sample (as reported): 53 · Recorded unit: Not reported · Clinical comparison of the efficacy of spirulina platensis and cetirizine for treatment of allergic rhinitis · Randomized Controlled Trial · rct · PMID 32773785 +8 more outcomes →

Important: This page reflects observational, aggregate-only community reporting and independent published research. It is not medical advice, and it does not claim any compound treats, cures, or is effective for any condition. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or treatment.

No community reports published yet.

We publish allergies results only once at least 10 people report on the same compound, so no individual report is ever shown.

Spirulina
Research saysResearch score 55/100 · Moderate3 of 3 studies reported at least one benefit
People reportNot published yet — needs 10 or more reports