Community observations, not medical advice.Always speak with a qualified healthcare professional.
Hormone Health

PCOS

About PCOS — Hormone Health.

Polycystic ovary syndrome — hormonal imbalance, irregular cycles, insulin resistance, and fertility issues.

1studies analysed
1compounds with evidence
Randomised trialstrongest evidence
Where research is strongest
  1. Inositol 44
Add your outcome — free & pseudonymous

Tried something for PCOS? Share how it went — only ever published as part of a group of 10+.

1linked compounds
11linked studies
0published community reports

Headline results for PCOS.

Figures as the studies reported them.

Colour keyReported a benefitNo clear benefitUnclearPossible harmAmber is for highlights, such as where the most research is. It never means a result was good.

5of 5

Inositol

5 of 5 results reported a benefit

1 randomised trial, 137 people

  • Acne severityReported a benefitmeasurement not reportedMyo-inositol and D-chiro inositol significantly improved acne score compared with placebo over 6 months.1 randomised trial2015 study ↗

No figure given: Hormone levels (reported a benefit); Menstrual cycle regularity (reported a benefit).

Also measured alongside: Insulin resistance (reported a benefit); Metabolic markers (reported a benefit).

Every result

Where the evidence is concentrated.

Published research

PCOS: findings by compound

What this means: Bars count reported findings, not treatment effectiveness or certainty.

One study may report several findings or appear in more than one pairing. Counts do not show the size of an effect. Comparable numerical estimates are not established for this summary.

View the full data table
Published research: reported directions by pairing
Compound and conditionFindings (count)Studies (count)Reported results (finding counts)How sure?
Inositol51Benefit: 5; no benefit: 0; harm: 0; unclear: 0; not recorded / unrecognised: 0Not formally graded

Degree of benefit for Pcos

Strongest evidence first.

Published research: Pcos. Study design is not a certainty grade.
CompoundStudy designsReported findings
InositolResearch score 44/100 · Limited1 randomised trial — 1 study5/5 outcomes showed benefit
  • Acne scoreReported a benefit — measurement not reportedbenefit2015 study ↗
    Exact figuresn=137 · Follow-up: 6 months · Sample (as reported): 137 · Recorded unit: Not reported · Myo-inositol vs. D-chiro inositol in PCOS treatment. · Randomized Controlled Trial · rct · PMID 25670222
  • Endocrine parametersReported a benefit — measurement not reportedbenefit2015 study ↗
    Exact figuresn=137 · Follow-up: 6 months · Sample (as reported): 137 · Recorded unit: Not reported · Myo-inositol vs. D-chiro inositol in PCOS treatment. · Randomized Controlled Trial · rct · PMID 25670222
  • Insulin resistance — how well the body responds to insulinReported a benefit — measurement not reportedbenefit2015 study ↗
    Exact figuresn=137 · Follow-up: 6 months · Sample (as reported): 137 · Recorded unit: Not reported · Myo-inositol vs. D-chiro inositol in PCOS treatment. · Randomized Controlled Trial · rct · PMID 25670222
  • Menstrual cycle regularityReported a benefit — measurement not reportedbenefit2015 study ↗
    Exact figuresn=137 · Follow-up: 6 months · Sample (as reported): 137 · Recorded unit: Not reported · Myo-inositol vs. D-chiro inositol in PCOS treatment. · Randomized Controlled Trial · rct · PMID 25670222
+1 more outcome →
Important: This page reflects observational, aggregate-only community reporting and independent published research. It is not medical advice, and it does not claim any compound treats, cures, or is effective for any condition. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or treatment.

No community reports published yet.

We publish pcos results only once at least 10 people report on the same compound, so no individual report is ever shown.

  • Inositol

    Research saysResearch score 44/100 · Limited1 of 1 study reported at least one benefit
    People reportNot published yet — needs 10 or more reports

Used something for pcos? Share how it went — only ever published in a group of 10 or more.

Add your outcome

Peer-reviewed research.

Every study behind the numbers above is linked next to its result.

10 more papers, not summarised above

Strongest evidence first.

01Comparison of metformin with inositol versus metformin alone in women with polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trialsKelly FA, et al. · Endocrine · 2025

Systematic Review · matched via Pcos · PubMed record (CORPUS-A)

PMID 39331347 ↗
02Inositol for Polycystic Ovary Syndrome: A Systematic Review and Meta-analysis to Inform the 2023 Update of the International Evidence-based PCOS GuidelinesFitz V, et al. · The Journal of clinical endocrinology and metabolism · 2024

Systematic Review · matched via Pcos · PubMed record (CORPUS-A)

PMID 38163998 ↗
03Polycystic ovaries and herbal remedies: A systematic reviewManouchehri A, et al. · JBRA assisted reproduction · 2023

Systematic Review · matched via Pcos · PubMed record (CORPUS-A)

PMID 35916457 ↗
04Inositol is an effective and safe treatment in polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trialsGreff D, et al. · Reproductive biology and endocrinology : RB&E · 2023

Meta-Analysis · matched via Pcos · PubMed record (CORPUS-A)

PMID 36703143 ↗
05Comparative efficacy of combined myo-inositol and D-chiro inositol versus metformin across PCOS Phenotypes: enhancing ovarian function, ovulation, and stress response in a prospective clinical trialGul M, et al. · Naunyn-Schmiedeberg's archives of pharmacology · 2025

Randomized Controlled Trial · matched via Pcos · PubMed record (CORPUS-A)

PMID 39847053 ↗
06Myo-inositol Supplementation to Prevent Pregnancy Complications in Polycystic Ovary Syndrome: A Randomized Clinical Trialvan der Wel AWT, et al. · JAMA · 2025

Randomized Controlled Trial · matched via Pcos · PubMed record (CORPUS-A)

PMID 40920401 ↗
07A randomized controlled trial comparing myoinositol with metformin versus metformin monotherapy in polycystic ovary syndromeNazirudeen R, et al. · Clinical endocrinology · 2023

Randomized Controlled Trial · matched via Pcos · PubMed record (CORPUS-A)

PMID 37265016 ↗
08Treatment of lean PCOS teenagers: a follow-up comparison between Myo-Inositol and oral contraceptivesPkhaladze L, et al. · European review for medical and pharmacological sciences · 2021

Randomized Controlled Trial · matched via Pcos · PubMed record (CORPUS-A)

PMID 34919250 ↗
09Comparison of two insulin sensitizers, metformin and myo-inositol, in women with polycystic ovary syndrome (PCOS)Fruzzetti F, et al. · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2017

Randomized Controlled Trial · matched via Pcos · PubMed record (CORPUS-A)

PMID 27808588 ↗
10Myo-inositol for PCOS: A systematic review and meta-analysisUnuane D et al. · Reprod Biomed Online · 2023

Myo-inositol improved ovulation rates, insulin sensitivity, and androgen levels in PCOS.

PMID 32134487 ↗
Important: Studies vary in quality and relevance. We do not interpret them or give medical advice.

Linked compounds.

Position is not a recommendation. Scores summarise published studies only.