Polycystic ovary syndrome — hormonal imbalance, irregular cycles, insulin resistance, and fertility issues.
Compounds with published trial evidence for this condition, ranked by strength of evidence. Numbers come from the trial reports themselves — see each study via its PMID.
| Compound | Evidence strength | What trials suggest | Study |
|---|---|---|---|
| Inositol | 1 randomised trial outcome | Myo-inositol and D-chiro inositol significantly improved acne score compared with placebo over 6 months.5/1 outcomes showed benefit | PMID 25670222 |
Audited published findings per compound. Dark green = benefit findings; full bar = all findings. Drill into a pair for the breakdown.
These compounds appear in related research or traditional use. Their position is not a recommendation or ranking.
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Randomized Controlled Trial · matched via Pcos · PubMed record (CORPUS-A)
PMID 39847053 ↗02Comparison of metformin with inositol versus metformin alone in women with polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trialsKelly FA, et al. · Endocrine · 2025Systematic Review · matched via Pcos · PubMed record (CORPUS-A)
PMID 39331347 ↗03Myo-inositol Supplementation to Prevent Pregnancy Complications in Polycystic Ovary Syndrome: A Randomized Clinical Trialvan der Wel AWT, et al. · JAMA · 2025Randomized Controlled Trial · matched via Pcos · PubMed record (CORPUS-A)
PMID 40920401 ↗04Inositol for Polycystic Ovary Syndrome: A Systematic Review and Meta-analysis to Inform the 2023 Update of the International Evidence-based PCOS GuidelinesFitz V, et al. · The Journal of clinical endocrinology and metabolism · 2024Systematic Review · matched via Pcos · PubMed record (CORPUS-A)
PMID 38163998 ↗05Myo-inositol for PCOS: A systematic review and meta-analysisUnuane D et al. · Reprod Biomed Online · 2023Myo-inositol improved ovulation rates, insulin sensitivity, and androgen levels in PCOS.
PMID 32134487 ↗Meta-Analysis · matched via Pcos · PubMed record (CORPUS-A)
Outcome summaries extracted from the linked papers' curated records. Educational, not medical advice.
Figures are reported as published; study designs and populations vary. Works for Us does not interpret results or provide medical advice.