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herb × Mental Health

Ashwagandha KSM-66 for Stress

Full-spectrum ashwagandha root extract standardised for withanolide content using a low-temperature aqueous extraction process; the most heavily trialled ashwagandha formulation for cortisol reduction and stress resilience.

-published research: study records
-published research: findings
Not formally gradedcertainty of the research
On this pageOverviewEvidenceCommunity outcomesRelated
Why Ashwagandha KSM-66 for Stress?

The connection

Chronic stress, burnout and high cortisol — distinct from anxiety.

Also known as: KSM-66 Ashwagandha

Published research

Ashwagandha KSM-66 × Stress: at a glance

Every published result for this pair, extracted and audited.

Published research

Ashwagandha KSM-66 / Stress: publication years

What this means: Counts describe research quantity, not treatment effectiveness or certainty.

Ashwagandha KSM-66 / Stress: publication years (publications, count)
CategoryPublications (count)
20253
20263
← Zoom out: all evidence for Ashwagandha KSM-66Zoom out: compare compounds for Stress →
Published research

Ashwagandha KSM-66 × Stress: the evidence base

Hand-selected PubMed studies, linked to the originals.

6studies referenced
6journals
2025–2026publication range

Ordered by strength of evidence, then result direction.

01Potential Bioactive Function of Microbial Metabolites as Inhibitors of Tyrosinase: A Systematic ReviewBarcenas-Giraldo S, et al. · International journal of molecular sciences · 2026PMID 41596661 ↗02Effects of ashwagandha (Withania somnifera) on mental health in adults: A systematic review and dose-response meta-analysis of randomized controlled trialsAlsanie SA, et al. · Complementary therapies in medicine · 2026PMID 41644067 ↗03Mechanism of Ganoderma lucidum polysaccharides in the mangement of diabetes and its complicationsXin Y, et al. · Frontiers in pharmacology · 2026PMID 42147328 ↗04Edible and Medicinal Fungi as Candidate Natural Antidepressants: Mechanisms and Nutritional ImplicationsGong P, et al. · Molecular nutrition & food research · 2025PMID 40289452 ↗05Levodopa and Plant-Derived Bioactive Compounds in Parkinson's Disease: Mechanisms, Efficacy, and Future PerspectivesAktaş E, et al. · CNS neuroscience & therapeutics · 2025PMID 40808332 ↗06Transcriptome-based meta-analysis of drought stress regulatory genes in tomatoMurtaza M, et al. · BMC plant biology · 2025PMID 41068586 ↗
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Community experiences

Contributors volunteered; this does not establish treatment effectiveness or population incidence.

Reported changes

No publishable community breakdown is available. This does not establish that no reports exist.

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Important: This page reflects observational, aggregate-only community reporting and independent published research. It is not medical advice, and it does not claim any compound treats, cures, or is effective for any condition. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or treatment.