Cannabis (THC) for Sleep Issues
Delta-9-tetrahydrocannabinol, the primary psychoactive cannabinoid in Cannabis sativa, acting as a partial agonist at CB1 receptors; used medically for chronic pain, chemotherapy-induced nausea, appetite stimulation, and spasticity. Subject to legal restrictions varying by jurisdiction.
The connection
Difficulty falling asleep, staying asleep, or poor sleep quality. Insomnia affects ~30% of adults.
Also known as: THC, Delta-9-tetrahydrocannabinol, Marijuana, Cannabis sativa
Cannabis (THC) × Sleep Issues: at a glance
Every published result for this pair, extracted and audited.
Cannabis (THC) / Sleep Issues: publication years
What this means: Counts describe research quantity, not treatment effectiveness or certainty.
| Category | Publications (count) |
|---|---|
| 2024 | 3 |
| 2025 | 1 |
| 2026 | 2 |
Cannabis (THC) × Sleep Issues: the evidence base
Hand-selected PubMed studies, linked to the originals.
Ordered by strength of evidence, then result direction.
01Cannabis-Based Products for Chronic Pain : An Updated Systematic ReviewChou R, et al. · Annals of internal medicine · 2026PMID 41429020 ↗02The effects of oral cannabidiol supplementation on blood pressure in adults: a systematic review of randomised controlled trialsRoberts A, et al. · Journal of cannabis research · 2026PMID 42321899 ↗03Dysregulation of melatonin rhythm in Parkinson's and Huntington's disease: a systematic review and meta-analysisSuram RP, et al. · Frontiers in aging neuroscience · 2025PMID 41143249 ↗04Effectiveness of Cannabidiol to Manage Chronic Pain: A Systematic ReviewMohammed SYM, et al. · Pain management nursing : official journal of the American Society of Pain Management Nurses · 2024PMID 37953193 ↗05Cannabis and Cannabinoids in Adults With Cancer: ASCO GuidelineBraun IM, et al. · Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024PMID 38478773 ↗06Effects of Dietary Supplementation in Patients with Restless Legs Syndrome: A Systematic ReviewGonzález-Parejo P, et al. · Nutrients · 2024PMID 39064758 ↗Community experiences
Contributors volunteered; this does not establish treatment effectiveness or population incidence.
Reported changes
No publishable community breakdown is available. This does not establish that no reports exist.