MSM (Methylsulfonylmethane) for Back Pain
Organic sulphur compound providing a bioavailable sulphur source for collagen and keratin synthesis; studied for joint pain, exercise-induced muscle soreness, and allergy symptoms, usually alongside glucosamine.
The connection
Pain in the lower, mid, or upper back. Often muscular but can involve disc, nerve, or joint issues.
Also known as: MSM, Organic sulphur
MSM (Methylsulfonylmethane) × Back Pain: at a glance
Every published result for this pair, extracted and audited.
MSM (Methylsulfonylmethane) / Back Pain: publication years
What this means: Counts describe research quantity, not treatment effectiveness or certainty.
| Category | Publications (count) |
|---|---|
| 2008 | 1 |
| 2023 | 1 |
| 2025 | 3 |
| 2026 | 1 |
MSM (Methylsulfonylmethane) × Back Pain: the evidence base
Hand-selected PubMed studies, linked to the originals.
Ordered by strength of evidence, then result direction.
01Efficacy and Safety of Anti-nerve Growth Factor Monoclonal Antibodies in Managing Chronic Musculoskeletal Pain: A Systematic Review with Network Meta-analysisAbouelella A, et al. · Drugs · 2026PMID 41880116 ↗02Efficacy of dietary supplements for treating knee osteoarthritis: a systematic review and network meta-analysisDu P, et al. · Frontiers in nutrition · 2025PMID 40123938 ↗03A large meta-analysis identifies genes associated with anterior uveitisGelfman S, et al. · Nature communications · 2023PMID 37949852 ↗04Systematic review of the nutritional supplements dimethyl sulfoxide (DMSO) and methylsulfonylmethane (MSM) in the treatment of osteoarthritisBrien S, et al. · Osteoarthritis and cartilage · 2008PMID 18417375 ↗05Using the Rise and Fall of Oxidative Stress and Inflammation Post-Exercise to Evaluate the Effect of Methylsulfonylmethane Supplementation on Immune Response mRNAMcFarlin BK, et al. · Nutrients · 2025PMID 40507030 ↗06[Combination therapy for exacerbations of pain in osteoarthritis with non-fixed combinations]Naumov AV, et al. · Terapevticheskii arkhiv · 2025PMID 40561485 ↗Community experiences
Contributors volunteered; this does not establish treatment effectiveness or population incidence.
Reported changes
No publishable community breakdown is available. This does not establish that no reports exist.