Community observations, not medical advice.Always speak with a qualified healthcare professional.
supplement × Mental Health

Phosphatidylserine for Stress

Phospholipid concentrated in neuronal cell membranes, now typically sourced from soy or sunflower lecithin; small trials suggest a reduced cortisol response to exercise stress and modest cognitive benefit in age-related decline.

-published research: study records
-published research: findings
Not formally gradedcertainty of the research
On this pageOverviewEvidenceCommunity outcomesRelated
Why Phosphatidylserine for Stress?

The connection

Chronic stress, burnout and high cortisol — distinct from anxiety.

Also known as: PS, Soy phosphatidylserine

Published research

Phosphatidylserine × Stress: at a glance

Every published result for this pair, extracted and audited.

Published research

Phosphatidylserine / Stress: publication years

What this means: Counts describe research quantity, not treatment effectiveness or certainty.

Phosphatidylserine / Stress: publication years (publications, count)
CategoryPublications (count)
20253
20263
← Zoom out: all evidence for PhosphatidylserineZoom out: compare compounds for Stress →
Published research

Phosphatidylserine × Stress: the evidence base

Hand-selected PubMed studies, linked to the originals.

6studies referenced
6journals
2025–2026publication range

Ordered by strength of evidence, then result direction.

01Potential Bioactive Function of Microbial Metabolites as Inhibitors of Tyrosinase: A Systematic ReviewBarcenas-Giraldo S, et al. · International journal of molecular sciences · 2026PMID 41596661 ↗02Effects of ashwagandha (Withania somnifera) on mental health in adults: A systematic review and dose-response meta-analysis of randomized controlled trialsAlsanie SA, et al. · Complementary therapies in medicine · 2026PMID 41644067 ↗03Mechanism of Ganoderma lucidum polysaccharides in the mangement of diabetes and its complicationsXin Y, et al. · Frontiers in pharmacology · 2026PMID 42147328 ↗04Effects of acute exercise on cognitive function: A meta-review of 30 systematic reviews with meta-analysesChang YK, et al. · Psychological bulletin · 2025PMID 39883421 ↗05Edible and Medicinal Fungi as Candidate Natural Antidepressants: Mechanisms and Nutritional ImplicationsGong P, et al. · Molecular nutrition & food research · 2025PMID 40289452 ↗06Levodopa and Plant-Derived Bioactive Compounds in Parkinson's Disease: Mechanisms, Efficacy, and Future PerspectivesAktaş E, et al. · CNS neuroscience & therapeutics · 2025PMID 40808332 ↗
Search PubMed ↗View on PubChem ↗Find clinical trials ↗

Community experiences

Contributors volunteered; this does not establish treatment effectiveness or population incidence.

Reported changes

No publishable community breakdown is available. This does not establish that no reports exist.

Share your experience
Important: This page reflects observational, aggregate-only community reporting and independent published research. It is not medical advice, and it does not claim any compound treats, cures, or is effective for any condition. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or treatment.