Compound library
Understand what people are taking.
Browse medicines, supplements, herbs, and health foods. Each profile brings community reports and linked research into one clear view.
Browse medicines, supplements, herbs, and health foods. Each profile brings community reports and linked research into one clear view.
Soluble, gel-forming fibre from the seed husk of Plantago ovata (ispaghula). Meta-analyses of 28 and 29 randomised trials found it lowers LDL ('bad') cholesterol by about 0.33-0.35 mmol/L, and pooled trials show lower fasting blood sugar and HbA1c, mostly in people who already have type 2 diabetes. Reviews of its effect on body weight disagree.
5 of 5 results reported a benefit, from 2 published studies.
2 studies, including a review of trials
These are the figures the studies reported, not a prediction for any one person. Where several studies measured the same thing in the same unit, we show a simple average and say so. Every individual result is listed below.
See every resultLDL, HDL, triglycerides, and lipid profile management.
Also known as: Psyllium, Ispaghula, Plantago ovata
Every published result for this pair, extracted and audited.
These charts group published studies by what they reported and how they were run — green marks studies that reported a benefit for this pairing. Tiers run from pooled analyses of many trials (strongest) to one-off observational reports.
Direction of reported outcomes for Psyllium Husk in cholesterol.
Study designs behind these findings.
Hand-selected PubMed studies, linked to the originals.
Ordered by strength of evidence, then result direction.
01Clinical Efficacy of Curcumin, Resveratrol, Silymarin, and Berberine on Cardio-Metabolic Risk Factors Among Patients With Type 2 Diabetes Mellitus: A Systemic Review and Bayesian Network Meta-AnalysisMiao R, et al. · Phytotherapy research : PTR · 2025PMID 40439602 ↗02Efficacy and safety of berberine on the components of metabolic syndrome: a systematic review and meta-analysis of randomized placebo-controlled trialsLiu D, et al. · Frontiers in pharmacology · 2025PMID 40740996 ↗03The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic reviewNie Q, et al. · Journal of translational medicine · 2024PMID 38429794 ↗04Overall and Sex-Specific Effect of Berberine for the Treatment of Dyslipidemia in Adults: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled TrialsBe the first to share what you noticed with Psyllium Husk for cholesterol. Why counts start empty.
Every measured outcome, one row per finding - numbers exactly as reported.
| Study | Design | n | Duration | Outcome measured | Reported result | Direction |
|---|---|---|---|---|---|---|
| PMID 38688104 2024 | Systematic review | 2769 | - | low-density lipoprotein cholesterol (LDL-C) | 0.35 mmol/L | Benefit |
| PMID 38688104 2024 | Systematic review | 2769 | - | total cholesterol (TC) | 0.28 mmol/L | Benefit |
| PMID 30239559 2018 | Meta-analysis | 1924 | - | apolipoprotein B (apoB) | -0.05 g/L (95% CI: -0.08, -0.03 g/L; P < 0.0001) | Benefit |
| PMID 30239559 2018 | Meta-analysis | 1924 | - | LDL cholesterol | -0.33 mmol/L (95% CI: -0.38, -0.27 mmol/L; P < 0.00001) | Benefit |
| PMID 30239559 2018 | Meta-analysis | 1924 | - | non-HDL cholesterol | -0.39 mmol/L (95% CI: -0.50, -0.27 mmol/L; P < 0.00001) | Benefit |