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LDL, HDL, triglycerides, and lipid profile management.
Compounds with published trial evidence for this condition, ranked by strength of evidence. Numbers come from the trial reports themselves — see each study via its PMID.
| Compound | Evidence strength | What trials suggest | Study |
|---|---|---|---|
| Berberine | 1 systematic review/meta-analysis outcome | Berberine reduced apolipoprotein B by 0.25 g/L vs placebo in 127 participants over 4 to 24 weeks.19/3 outcomes showed benefit | PMID 36941490 |
Audited published findings per compound. Dark green = benefit findings; full bar = all findings. Drill into a pair for the breakdown.
These compounds appear in related research or traditional use. Their position is not a recommendation or ranking.
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Open the original papers, check their methods, and discuss what is relevant with a qualified professional.
Systematic Review · matched via Cholesterol · PubMed record (CORPUS-A)
PMID 40740996 ↗02Clinical Efficacy of Curcumin, Resveratrol, Silymarin, and Berberine on Cardio-Metabolic Risk Factors Among Patients With Type 2 Diabetes Mellitus: A Systemic Review and Bayesian Network Meta-AnalysisMiao R, et al. · Phytotherapy research : PTR · 2025Systematic Review · matched via Cholesterol · PubMed record (CORPUS-A)
PMID 40439602 ↗03The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic reviewNie Q, et al. · Journal of translational medicine · 2024Meta-Analysis · matched via Cholesterol · PubMed record (CORPUS-A)
PMID 38429794 ↗04Berberine lowers cholesterol: A meta-analysisDong H et al. · Evid Based Complement Alternat Med · 2023Berberine lowered total cholesterol and LDL-C significantly across 11 RCTs.
PMID 23401702 ↗05Overall and Sex-Specific Effect of Berberine for the Treatment of Dyslipidemia in Adults: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled TrialsBlais JE, et al. · Drugs · 2023Meta-Analysis · matched via Cholesterol · PubMed record (CORPUS-A)
PMID 36941490 ↗06Network Meta-Analysis · matched via Cholesterol · PubMed record (CORPUS-A)
Outcome summaries extracted from the linked papers' curated records. Educational, not medical advice.
Figures are reported as published; study designs and populations vary. Works for Us does not interpret results or provide medical advice.