- Pain severity and treatment responseReported a benefitmeasurement not reportedSynthetic high THC products may moderately improve pain severity and response versus placebo in 1740 people over 1 to 6 months.1 review of trials2022 study ↗
Physical Health
Chronic Pain
About Chronic Pain — Physical Health.
Persistent pain lasting longer than 3 months. Can stem from injury, inflammation, or nervous system dysfunction.
1studies analysed
1compounds with evidence
Systematic reviewstrongest evidence
Where research is strongest
Add your outcome — free & pseudonymous
Tried something for Chronic Pain? Share how it went — only ever published as part of a group of 10+.
5linked compounds
8linked studies
0published community reports
Headline results for Chronic Pain.
Figures as the studies reported them.
Colour keyReported a benefitNo clear benefitUnclearPossible harmAmber is for highlights, such as where the most research is. It never means a result was good.
Where the evidence is concentrated.
Chronic Pain: findings by compound
What this means: Bars count reported findings, not treatment effectiveness or certainty.
One study may report several findings or appear in more than one pairing. Counts do not show the size of an effect. Comparable numerical estimates are not established for this summary.
View the full data table
| Compound and condition | Findings (count) | Studies (count) | Reported results (finding counts) | How sure? |
|---|---|---|---|---|
| Cannabis THC | 4 | 1 | Benefit: 1; no benefit: 0; harm: 3; unclear: 0; not recorded / unrecognised: 0 | Not formally graded |
Degree of benefit for Chronic Pain
Strongest evidence first.
| Compound | Study designs | Reported findings |
|---|---|---|
| Cannabis THCResearch score 13/100 · Mixed/Weak | 1 systematic review/meta-analysis — 1 study | 1/4 outcomes showed benefit
|
Important: This page reflects observational, aggregate-only community reporting and independent published research. It is not medical advice, and it does not claim any compound treats, cures, or is effective for any condition. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or treatment.
No community reports published yet.
We publish chronic pain results only once at least 10 people report on the same compound, so no individual report is ever shown.
Cannabis THC
Research saysResearch score 13/100 · Mixed/Weak1 of 1 study reported at least one benefitPeople reportNot published yet — needs 10 or more reports
Used something for chronic pain? Share how it went — only ever published in a group of 10 or more.
Add your outcomePeer-reviewed research.
Every study behind the numbers above is linked next to its result.
7 more papers, not summarised above
Strongest evidence first.
01Cannabis-Based Products for Chronic Pain : An Updated Systematic ReviewChou R, et al. · Annals of internal medicine · 2026Systematic Review · matched via Chronic Pain · PubMed record (CORPUS-A)
PMID 41429020 ↗02Effectiveness of Cannabidiol to Manage Chronic Pain: A Systematic ReviewMohammed SYM, et al. · Pain management nursing : official journal of the American Society of Pain Management Nurses · 2024Systematic Review · matched via Chronic Pain · PubMed record (CORPUS-A)
PMID 37953193 ↗03Evidence-Based Treatment of Pain in Chemotherapy-Induced Peripheral NeuropathyD'Souza RS, et al. · Current pain and headache reports · 2023Systematic Review · matched via Chronic Pain · PubMed record (CORPUS-A)
PMID 37058254 ↗04Medical cannabinoids: a pharmacology-based systematic review and meta-analysis for all relevant medical indicationsBilbao A, et al. · BMC medicine · 2022Meta-Analysis · matched via Chronic Pain · PubMed record (CORPUS-A)
PMID 35982439 ↗05Medical cannabis or cannabinoids for chronic non-cancer and cancer related pain: a systematic review and meta-analysis of randomised clinical trialsWang L, et al. · BMJ (Clinical research ed.) · 2021Meta-Analysis · matched via Chronic Pain · PubMed record (CORPUS-A)
PMID 34497047 ↗06Opioids for Chronic Noncancer Pain: A Systematic Review and Meta-analysisBusse JW, et al. · JAMA · 2018Meta-Analysis · matched via Chronic Pain · PubMed record (CORPUS-A)
PMID 30561481 ↗07Cannabinoids for Medical Use: A Systematic Review and Meta-analysisWhiting PF, et al. · JAMA · 2015Meta-Analysis · matched via Chronic Pain · PubMed record (CORPUS-A)
PMID 26103030 ↗Important: Studies vary in quality and relevance. We do not interpret them or give medical advice.
Linked compounds.
Position is not a recommendation. Scores summarise published studies only.