Bone density, osteoporosis prevention, fracture recovery.
Compounds with published trial evidence for this condition, ranked by strength of evidence. Numbers come from the trial reports themselves — see each study via its PMID.
| Compound | Evidence strength | What trials suggest | Study |
|---|---|---|---|
| Vitamin D3 | 1 randomised trial outcome | Vitamin D3 did not significantly lower hip fracture risk vs placebo in 25,871 adults over a median of 5.3 years.0/1 outcomes showed benefit | PMID 35939577 |
Audited published findings per compound. Dark green = benefit findings; full bar = all findings. Drill into a pair for the breakdown.
These compounds appear in related research or traditional use. Their position is not a recommendation or ranking.
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Open the original papers, check their methods, and discuss what is relevant with a qualified professional.
Systematic Review · matched via Bone Health · PubMed record (CORPUS-A)
PMID 38180112 ↗02Effects of vitamin D3, omega-3s, and a simple strength training exercise program on bone health: the DO-HEALTH randomized controlled trialKistler-Fischbacher M, et al. · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2024Randomized Controlled Trial · matched via Bone Health · PubMed record (CORPUS-A)
PMID 38613445 ↗03Vitamin D and calcium for fracture prevention: A meta-analysisWeaver CM et al. · Osteoporos Int · 2023Combined vitamin D and calcium supplementation reduced fracture risk by 15% in older adults.
PMID 24122081 ↗04Supplementation of vitamin D isolated or calcium-associated with bone remodeling and fracture risk in postmenopausal women without osteoporosis: A systematic review of randomized clinical trialsReis AR, et al. · Nutrition (Burbank, Los Angeles County, Calif.) · 2023Systematic Review · matched via Bone Health · PubMed record (CORPUS-A)
PMID 37544189 ↗05What is the impact of daily oral supplementation of vitamin D3 (cholecalciferol) plus calcium on the incidence of hip fracture in older people? A systematic review and meta-analysisManoj P, et al. · International journal of older people nursing · 2023Meta-Analysis · matched via Bone Health · PubMed record (CORPUS-A)
PMID 35842938 ↗Outcome summaries extracted from the linked papers' curated records. Educational, not medical advice.
Figures are reported as published; study designs and populations vary. Works for Us does not interpret results or provide medical advice.