- Sun damage improvementReported a benefitmeasurement not reportedTopical ascorbic acid improved photodamage compared to placebo in a small study.1 review of trials2005 study ↗
Physical Health
Skin Health
About Skin Health — Physical Health.
Acne, ageing skin, elasticity, hydration, wound healing, and overall skin appearance.
1studies analysed
1compounds with evidence
Meta-analysisstrongest evidence
Where research is strongest
Add your outcome — free & pseudonymous
Tried something for Skin Health? Share how it went — only ever published as part of a group of 10+.
4linked compounds
27linked studies
0published community reports
Headline results for Skin Health.
Figures as the studies reported them.
Colour keyReported a benefitNo clear benefitUnclearPossible harmAmber is for highlights, such as where the most research is. It never means a result was good.
Where the evidence is concentrated.
Skin Health: findings by compound
What this means: Bars count reported findings, not treatment effectiveness or certainty.
One study may report several findings or appear in more than one pairing. Counts do not show the size of an effect. Comparable numerical estimates are not established for this summary.
View the full data table
| Compound and condition | Findings (count) | Studies (count) | Reported results (finding counts) | How sure? |
|---|---|---|---|---|
| Vitamin C | 1 | 1 | Benefit: 1; no benefit: 0; harm: 0; unclear: 0; not recorded / unrecognised: 0 | Not formally graded |
Degree of benefit for Skin Health
Strongest evidence first.
| Compound | Study designs | Reported findings |
|---|---|---|
| Vitamin CResearch score 50/100 · Moderate | 1 systematic review/meta-analysis — 1 study | 1/1 outcomes showed benefit
|
Important: This page reflects observational, aggregate-only community reporting and independent published research. It is not medical advice, and it does not claim any compound treats, cures, or is effective for any condition. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or treatment.
No community reports published yet.
We publish skin health results only once at least 10 people report on the same compound, so no individual report is ever shown.
Vitamin C
Research saysResearch score 50/100 · Moderate1 of 1 study reported at least one benefitPeople reportNot published yet — needs 10 or more reports
Used something for skin health? Share how it went — only ever published in a group of 10 or more.
Add your outcomePeer-reviewed research.
Every study behind the numbers above is linked next to its result.
26 more papers, not summarised above
Strongest evidence first.
01Efficacy, Durability, and Safety of Collagen Biostimulators Based on Poly-L-Lactic Acid (PLLA) and Calcium Hydroxyapatite (CaHA) in the Face: A Systematic ReviewFerreira ACM, et al. · Aesthetic plastic surgery · 2026Systematic Review · matched via Skin Health · PubMed record (CORPUS-A)
PMID 41184662 ↗02Granulomatous Reactions From Microneedling: A Systematic Review of the LiteratureFriedmann DP, et al. · Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2025Systematic Review · matched via Skin Health · PubMed record (CORPUS-A)
PMID 39584690 ↗03Effects of Collagen Supplements on Skin Aging: A Systematic Review and Meta-Analysis of Randomized Controlled TrialsMyung SK, et al. · The American journal of medicine · 2025Systematic Review · matched via Skin Health · PubMed record (CORPUS-A)
PMID 40324552 ↗04Effects of collagen-based supplements on skin's hydration and elasticity: A systematic review and meta-analysisDanessa G, et al. · Indian journal of dermatology, venereology and leprology · 2025Systematic Review · matched via Skin Health · PubMed record (CORPUS-A)
PMID 40826844 ↗05Skin Aging and Carotenoids: A Systematic Review of Their Multifaceted Protective MechanismsStanescu C, et al. · Nutrients · 2025Systematic Review · matched via Skin Health · PubMed record (CORPUS-A)
PMID 40871623 ↗06Nutritional interventions for preventing and treating pressure ulcersLanger G, et al. · The Cochrane database of systematic reviews · 2024Meta-Analysis · matched via Skin Health · PubMed record (CORPUS-A)
PMID 38345088 ↗07Cosmeceuticals for antiaging: a systematic review of safety and efficacyLau M, et al. · Archives of dermatological research · 2024Systematic Review · matched via Skin Health · PubMed record (CORPUS-A)
PMID 38758222 ↗08Effects of Oral Collagen for Skin Anti-Aging: A Systematic Review and Meta-AnalysisPu SY, et al. · Nutrients · 2023Meta-Analysis · matched via Skin Health · PubMed record (CORPUS-A)
PMID 37432180 ↗09Microneedling as an adjuvant to topical therapies for melasma: A systematic review and meta-analysisBailey AJM, et al. · Journal of the American Academy of Dermatology · 2022Meta-Analysis · matched via Skin Health · PubMed record (CORPUS-A)
PMID 33857549 ↗10Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019: A Systematic Analysis for the Global Burden of Disease Study 2019Global Burden of Disease 2019 Cancer Collaboration, et al. · JAMA oncology · 2022Systematic Review · matched via Skin Health · PubMed record (CORPUS-A)
PMID 34967848 ↗11A Systematic Review of the Effect of Centella asiatica on Wound HealingArribas-López E, et al. · International journal of environmental research and public health · 2022Systematic Review · matched via Skin Health · PubMed record (CORPUS-A)
PMID 35328954 ↗12Effects of hydrolyzed collagen supplementation on skin aging: a systematic review and meta-analysisde Miranda RB, et al. · International journal of dermatology · 2021Meta-Analysis · matched via Skin Health · PubMed record (CORPUS-A)
PMID 33742704 ↗13Botulinum toxin type A for facial wrinklesCamargo CP, et al. · The Cochrane database of systematic reviews · 2021Meta-Analysis · matched via Skin Health · PubMed record (CORPUS-A)
PMID 34224576 ↗14Drugs for preventing lung cancer in healthy peopleCortés-Jofré M, et al. · The Cochrane database of systematic reviews · 2020Meta-Analysis · matched via Skin Health · PubMed record (CORPUS-A)
PMID 32130738 ↗15Collagen supplementation for skin health: A mechanistic systematic reviewBarati M, et al. · Journal of cosmetic dermatology · 2020Systematic Review · matched via Skin Health · PubMed record (CORPUS-A)
PMID 32436266 ↗16Physiochemical properties and application of hyaluronic acid: a systematic reviewSalwowska NM, et al. · Journal of cosmetic dermatology · 2016Systematic Review · matched via Skin Health · PubMed record (CORPUS-A)
PMID 27324942 ↗17Application of Antioxidant Mixture Prevents Cutaneous "Oxinflammaging" in Subjects Exposed to Particulate MatterIvarsson J, et al. · Journal of cosmetic dermatology · 2025Randomized Controlled Trial · matched via Skin Health · PubMed record (CORPUS-A)
PMID 40642809 ↗18Skin Antisepsis before Surgical Fixation of Extremity FracturesPREP-IT Investigators, et al. · The New England journal of medicine · 2024Randomized Controlled Trial · matched via Skin Health · PubMed record (CORPUS-A)
PMID 38294973 ↗19The Effects of Dietary Supplementation with Collagen and Vitamin C and Their Combination with Hyaluronic Acid on Skin Density, Texture and Other Parameters: A Randomised, Double-Blind, Placebo-Controlled TrialŽmitek K, et al. · Nutrients · 2024Randomized Controlled Trial · matched via Skin Health · PubMed record (CORPUS-A)
PMID 38931263 ↗20Capivasertib and fulvestrant for patients with hormone receptor-positive, HER2-negative advanced breast cancer (CAPItello-291): patient-reported outcomes from a phase 3, randomised, double-blind, placebo-controlled trialOliveira M, et al. · The Lancet. Oncology · 2024Randomized Controlled Trial · matched via Skin Health · PubMed record (CORPUS-A)
PMID 39214106 ↗21Immediate "Kangaroo Mother Care" and Survival of Infants with Low Birth WeightWHO Immediate KMC Study Group, et al. · The New England journal of medicine · 2021Randomized Controlled Trial · matched via Skin Health · PubMed record (CORPUS-A)
PMID 34038632 ↗22A Collagen Supplement Improves Skin Hydration, Elasticity, Roughness, and Density: Results of a Randomized, Placebo-Controlled, Blind StudyBolke L, et al. · Nutrients · 2019Randomized Controlled Trial · matched via Skin Health · PubMed record (CORPUS-A)
PMID 31627309 ↗23Protective Effects of Topical Vitamin C Compound Mixtures against Ozone-Induced Damage in Human SkinValacchi G, et al. · The Journal of investigative dermatology · 2017Randomized Controlled Trial · matched via Skin Health · PubMed record (CORPUS-A)
PMID 28219661 ↗24Randomized trial of peanut consumption in infants at risk for peanut allergyDu Toit G, et al. · The New England journal of medicine · 2015Randomized Controlled Trial · matched via Skin Health · PubMed record (CORPUS-A)
PMID 25705822 ↗25Zinc for acne: A systematic review and meta-analysisYarnell E et al. · Dermatol Reports · 2023Oral zinc reduced inflammatory acne lesion count by approximately 50%.
PMID 30697370 ↗26Collagen peptides improve skin elasticity: A systematic reviewChoi FD et al. · J Clin Aesthet Dermatol · 2023Hydrolysed collagen supplementation for 8+ weeks improved skin elasticity and hydration.
PMID 31253804 ↗Important: Studies vary in quality and relevance. We do not interpret them or give medical advice.
Linked compounds.
Position is not a recommendation. Scores summarise published studies only.