Physical Health

Joint Pain

Joint discomfort, inflammation, arthritis, and reduced mobility. Affects all ages, worsens with age.

4linked compounds

70linked studies

4compounds tracked

On this pageCompounds Community outcomes Research

Comparing compounds studied for Joint Pain

Compounds with published trial evidence for this condition, ranked by strength of evidence. Numbers come from the trial reports themselves — see each study via its PMID.

Compound	Evidence strength	What trials suggest	Study
Hyaluronic Acid	3 systematic review/meta-analysis outcomes	Hyaluronic acid injections significantly improved pain scores compared to corticosteroid injections in 1023 patients with shoulder osteoarthritis.7/3 outcomes showed benefit	PMID 37314198
CBD OIL	1 systematic review/meta-analysis outcome	Pain interference scores may have reduced by 1.52 points vs baseline in 117 dogs over 4-12 weeks, but evidence is very uncertain.3/2 outcomes showed benefit	PMID 37781283
Ginger	1 systematic review/meta-analysis outcome	No significant improvement in knee function with ginger capsules vs placebo was found.3/2 outcomes showed benefit	PMID 32214292
MSM	1 systematic review/meta-analysis outcome	Evidence for DMSO versus placebo in knee osteoarthritis pain was mixed and inconclusive due to methodological issues (n=681).1/2 outcomes showed benefit	PMID 18417375
Turmeric Curcumin	1 systematic review/meta-analysis outcome	Curcuma longa extract and curcumin had a lower incidence of adverse events compared to NSAIDs in 1621 participants.5/2 outcomes showed benefit	PMID 34017975
Omega 3	1 systematic review/meta-analysis outcome	Omega-3 did not significantly improve morning stiffness compared to placebo.1/1 outcomes showed benefit	PMID 22835600
Collagen Peptides	1 randomised trial outcome	Activity-related pain improved by 19.5 vs placebo in 139 people over 12 weeks.3/1 outcomes showed benefit	PMID 28177710
Glucosamine	1 randomised trial outcome	Adverse events were low and similarly distributed for CS+GH vs celecoxib over 6 months.0/1 outcomes showed benefit	PMID 25589511

Important: This page reflects observational, aggregate-only community reporting and independent published research. It is not medical advice, and it does not claim any compound treats, cures, or is effective for any condition. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or treatment.

Evidence analytics